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BPC-157 has shown interactions with vagal signaling in animal models, though the specifics of this interaction are still being characterized

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DeltaSleepInducing Peptide (DSIP): Science, Safety, and User Experience DeltaSleepInducing Peptide (DSIP) is a naturally occurring nonapeptide (TrpAlaGlyGlyAspAlaSerGlyGlu) first isolated from rabbit brain and produced in the human hypothalamus

doi:10.1371/journal.pone.0135268